The Vital Role of Black seeds (Nigella sativa) in Antagonize The side Effect of Green Lean Body Capsule on Liver Function in Female Rabbits

capsule) administration for 30 days on some liver function parameters and antagonize or decrease these effects by black seeds. Fifteen mature female rabbits randomly divided into three groups( 5 /group) drenched for 30 day: control group received physiological normal saline (1ml/kg B.W); first treated group T1 received green lean body capsule (4.2mg/kg B.W) ; second treated group T2 received green lean body capsule (4.2mg/kg B.W) and black seeds (28mg/kg B.W). Blood samples were collected via heart puncture pre treatment and day 30 of administration, the plasma liver function parameters reveled that green lean body capsule caused a significant increase in plasma total bilirubin, triglycerides, GOT and GPT enzymes, on the other hand decrease total cholesterol and glucose with un significant increase in total protein of T1 as compare to pretreatment, T2 and control while the T2 represented un significant changes in the above mentioned parameters as compare to pretreatment and control. In conclusions, the black seeds act as a defense factor against the destructive effect of green lean body capsule on the biochemical activity of hepatocyte.